rabbit polyclonal Search Results


anti polyclonal  (Abmart Inc)
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rabbit polyclonal antibody  (Affinity Biosciences)
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Affinity Biosciences rabbit polyclonal antibody
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rabbit polyclonal anti fsp 1 antibody  (Danaher Inc)
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polyclonal primary antibodies  (Bio-Rad)
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Bio-Rad polyclonal primary antibodies
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rabbit anti secretagogin  (BioVendor Instruments)
91
BioVendor Instruments rabbit anti secretagogin
A , B Confocal images of retinal sections from WT and α2δ4KO mice at ( A ). 2–4 months, and B >1 year stained with anti-PKC-α to label rod bipolar cells (RBCs). Scale bar, 50 μm. C Quantification of the total length of RBC dendritic sprouting within the ONL of WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). D , E Confocal images of WT and KO retinal sections at ( D ). 2–4 months, and E >1 year stained <t>with</t> <t>anti-secretagogin</t> (Scgn) to label cone bipolar cells (CBCs). Scale bar, 50 μm. F Quantification of total Scgn-positive dendritic sprouting within the ONL in WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). G , H Confocal images of WT and KO retinal sections at G . 2–4 months, and H >1 year stained with anti-PSD95 to label photoreceptor terminals. Scale bar, 50 μm. I Quantification of the PSD95-labeled area within the ONL of WT and KO retina at 2–4 months and >1 year (n = 4 mice per group). J,K . Confocal images of WT and KO retinal sections triple immunolabeled of PKC-α (green), vGlut1 (red), CTBP2 (blue) at ( J ) 2–4 months and ( K ) >1 year. Insets show higher magnification of retracted photoreceptor terminals colocalizing with sprouted RBC dendrites. Scale bar, 50 μm; inset, 5 μm. L , M Confocal images of WT and KO retinal sections triple immunolabeled of secretagogin (green), vGlut1 (blue), and CTBP2 (red) at L 2–4 months and ( M ) >1 year. Insets show higher magnification of retracted cone terminals colocalizing with sprouted CBC dendrites. Scale bar, 50 μm; inset, 5 μm. Error bars are SEM, unpaired t-test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 .
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rabbit igg  (Cedarlane)
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Cedarlane rabbit igg
A , B Confocal images of retinal sections from WT and α2δ4KO mice at ( A ). 2–4 months, and B >1 year stained with anti-PKC-α to label rod bipolar cells (RBCs). Scale bar, 50 μm. C Quantification of the total length of RBC dendritic sprouting within the ONL of WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). D , E Confocal images of WT and KO retinal sections at ( D ). 2–4 months, and E >1 year stained <t>with</t> <t>anti-secretagogin</t> (Scgn) to label cone bipolar cells (CBCs). Scale bar, 50 μm. F Quantification of total Scgn-positive dendritic sprouting within the ONL in WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). G , H Confocal images of WT and KO retinal sections at G . 2–4 months, and H >1 year stained with anti-PSD95 to label photoreceptor terminals. Scale bar, 50 μm. I Quantification of the PSD95-labeled area within the ONL of WT and KO retina at 2–4 months and >1 year (n = 4 mice per group). J,K . Confocal images of WT and KO retinal sections triple immunolabeled of PKC-α (green), vGlut1 (red), CTBP2 (blue) at ( J ) 2–4 months and ( K ) >1 year. Insets show higher magnification of retracted photoreceptor terminals colocalizing with sprouted RBC dendrites. Scale bar, 50 μm; inset, 5 μm. L , M Confocal images of WT and KO retinal sections triple immunolabeled of secretagogin (green), vGlut1 (blue), and CTBP2 (red) at L 2–4 months and ( M ) >1 year. Insets show higher magnification of retracted cone terminals colocalizing with sprouted CBC dendrites. Scale bar, 50 μm; inset, 5 μm. Error bars are SEM, unpaired t-test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 .
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secondary antibody conjugated to horseradish peroxidase hrp  (Cedarlane)
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Cedarlane secondary antibody conjugated to horseradish peroxidase hrp
A , B Confocal images of retinal sections from WT and α2δ4KO mice at ( A ). 2–4 months, and B >1 year stained with anti-PKC-α to label rod bipolar cells (RBCs). Scale bar, 50 μm. C Quantification of the total length of RBC dendritic sprouting within the ONL of WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). D , E Confocal images of WT and KO retinal sections at ( D ). 2–4 months, and E >1 year stained <t>with</t> <t>anti-secretagogin</t> (Scgn) to label cone bipolar cells (CBCs). Scale bar, 50 μm. F Quantification of total Scgn-positive dendritic sprouting within the ONL in WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). G , H Confocal images of WT and KO retinal sections at G . 2–4 months, and H >1 year stained with anti-PSD95 to label photoreceptor terminals. Scale bar, 50 μm. I Quantification of the PSD95-labeled area within the ONL of WT and KO retina at 2–4 months and >1 year (n = 4 mice per group). J,K . Confocal images of WT and KO retinal sections triple immunolabeled of PKC-α (green), vGlut1 (red), CTBP2 (blue) at ( J ) 2–4 months and ( K ) >1 year. Insets show higher magnification of retracted photoreceptor terminals colocalizing with sprouted RBC dendrites. Scale bar, 50 μm; inset, 5 μm. L , M Confocal images of WT and KO retinal sections triple immunolabeled of secretagogin (green), vGlut1 (blue), and CTBP2 (red) at L 2–4 months and ( M ) >1 year. Insets show higher magnification of retracted cone terminals colocalizing with sprouted CBC dendrites. Scale bar, 50 μm; inset, 5 μm. Error bars are SEM, unpaired t-test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 .
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fluorescein isothiocyanate conjugated polymorphonuclear leukocytes  (Cedarlane)
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Cedarlane fluorescein isothiocyanate conjugated polymorphonuclear leukocytes
A , B Confocal images of retinal sections from WT and α2δ4KO mice at ( A ). 2–4 months, and B >1 year stained with anti-PKC-α to label rod bipolar cells (RBCs). Scale bar, 50 μm. C Quantification of the total length of RBC dendritic sprouting within the ONL of WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). D , E Confocal images of WT and KO retinal sections at ( D ). 2–4 months, and E >1 year stained <t>with</t> <t>anti-secretagogin</t> (Scgn) to label cone bipolar cells (CBCs). Scale bar, 50 μm. F Quantification of total Scgn-positive dendritic sprouting within the ONL in WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). G , H Confocal images of WT and KO retinal sections at G . 2–4 months, and H >1 year stained with anti-PSD95 to label photoreceptor terminals. Scale bar, 50 μm. I Quantification of the PSD95-labeled area within the ONL of WT and KO retina at 2–4 months and >1 year (n = 4 mice per group). J,K . Confocal images of WT and KO retinal sections triple immunolabeled of PKC-α (green), vGlut1 (red), CTBP2 (blue) at ( J ) 2–4 months and ( K ) >1 year. Insets show higher magnification of retracted photoreceptor terminals colocalizing with sprouted RBC dendrites. Scale bar, 50 μm; inset, 5 μm. L , M Confocal images of WT and KO retinal sections triple immunolabeled of secretagogin (green), vGlut1 (blue), and CTBP2 (red) at L 2–4 months and ( M ) >1 year. Insets show higher magnification of retracted cone terminals colocalizing with sprouted CBC dendrites. Scale bar, 50 μm; inset, 5 μm. Error bars are SEM, unpaired t-test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 .
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horseradish peroxidase  (Cedarlane)
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Cedarlane horseradish peroxidase
A , B Confocal images of retinal sections from WT and α2δ4KO mice at ( A ). 2–4 months, and B >1 year stained with anti-PKC-α to label rod bipolar cells (RBCs). Scale bar, 50 μm. C Quantification of the total length of RBC dendritic sprouting within the ONL of WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). D , E Confocal images of WT and KO retinal sections at ( D ). 2–4 months, and E >1 year stained <t>with</t> <t>anti-secretagogin</t> (Scgn) to label cone bipolar cells (CBCs). Scale bar, 50 μm. F Quantification of total Scgn-positive dendritic sprouting within the ONL in WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). G , H Confocal images of WT and KO retinal sections at G . 2–4 months, and H >1 year stained with anti-PSD95 to label photoreceptor terminals. Scale bar, 50 μm. I Quantification of the PSD95-labeled area within the ONL of WT and KO retina at 2–4 months and >1 year (n = 4 mice per group). J,K . Confocal images of WT and KO retinal sections triple immunolabeled of PKC-α (green), vGlut1 (red), CTBP2 (blue) at ( J ) 2–4 months and ( K ) >1 year. Insets show higher magnification of retracted photoreceptor terminals colocalizing with sprouted RBC dendrites. Scale bar, 50 μm; inset, 5 μm. L , M Confocal images of WT and KO retinal sections triple immunolabeled of secretagogin (green), vGlut1 (blue), and CTBP2 (red) at L 2–4 months and ( M ) >1 year. Insets show higher magnification of retracted cone terminals colocalizing with sprouted CBC dendrites. Scale bar, 50 μm; inset, 5 μm. Error bars are SEM, unpaired t-test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 .
Horseradish Peroxidase, supplied by Cedarlane, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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sfxn5  (Cusabio)
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Cusabio sfxn5
A , B Confocal images of retinal sections from WT and α2δ4KO mice at ( A ). 2–4 months, and B >1 year stained with anti-PKC-α to label rod bipolar cells (RBCs). Scale bar, 50 μm. C Quantification of the total length of RBC dendritic sprouting within the ONL of WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). D , E Confocal images of WT and KO retinal sections at ( D ). 2–4 months, and E >1 year stained <t>with</t> <t>anti-secretagogin</t> (Scgn) to label cone bipolar cells (CBCs). Scale bar, 50 μm. F Quantification of total Scgn-positive dendritic sprouting within the ONL in WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). G , H Confocal images of WT and KO retinal sections at G . 2–4 months, and H >1 year stained with anti-PSD95 to label photoreceptor terminals. Scale bar, 50 μm. I Quantification of the PSD95-labeled area within the ONL of WT and KO retina at 2–4 months and >1 year (n = 4 mice per group). J,K . Confocal images of WT and KO retinal sections triple immunolabeled of PKC-α (green), vGlut1 (red), CTBP2 (blue) at ( J ) 2–4 months and ( K ) >1 year. Insets show higher magnification of retracted photoreceptor terminals colocalizing with sprouted RBC dendrites. Scale bar, 50 μm; inset, 5 μm. L , M Confocal images of WT and KO retinal sections triple immunolabeled of secretagogin (green), vGlut1 (blue), and CTBP2 (red) at L 2–4 months and ( M ) >1 year. Insets show higher magnification of retracted cone terminals colocalizing with sprouted CBC dendrites. Scale bar, 50 μm; inset, 5 μm. Error bars are SEM, unpaired t-test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 .
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rabbit anti mouse il 1a polyclonal serum  (Cedarlane)
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A , B Confocal images of retinal sections from WT and α2δ4KO mice at ( A ). 2–4 months, and B >1 year stained with anti-PKC-α to label rod bipolar cells (RBCs). Scale bar, 50 μm. C Quantification of the total length of RBC dendritic sprouting within the ONL of WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). D , E Confocal images of WT and KO retinal sections at ( D ). 2–4 months, and E >1 year stained <t>with</t> <t>anti-secretagogin</t> (Scgn) to label cone bipolar cells (CBCs). Scale bar, 50 μm. F Quantification of total Scgn-positive dendritic sprouting within the ONL in WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). G , H Confocal images of WT and KO retinal sections at G . 2–4 months, and H >1 year stained with anti-PSD95 to label photoreceptor terminals. Scale bar, 50 μm. I Quantification of the PSD95-labeled area within the ONL of WT and KO retina at 2–4 months and >1 year (n = 4 mice per group). J,K . Confocal images of WT and KO retinal sections triple immunolabeled of PKC-α (green), vGlut1 (red), CTBP2 (blue) at ( J ) 2–4 months and ( K ) >1 year. Insets show higher magnification of retracted photoreceptor terminals colocalizing with sprouted RBC dendrites. Scale bar, 50 μm; inset, 5 μm. L , M Confocal images of WT and KO retinal sections triple immunolabeled of secretagogin (green), vGlut1 (blue), and CTBP2 (red) at L 2–4 months and ( M ) >1 year. Insets show higher magnification of retracted cone terminals colocalizing with sprouted CBC dendrites. Scale bar, 50 μm; inset, 5 μm. Error bars are SEM, unpaired t-test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 .
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rabbit anti mouse ig  (Cedarlane)
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Cedarlane rabbit anti mouse ig
A , B Confocal images of retinal sections from WT and α2δ4KO mice at ( A ). 2–4 months, and B >1 year stained with anti-PKC-α to label rod bipolar cells (RBCs). Scale bar, 50 μm. C Quantification of the total length of RBC dendritic sprouting within the ONL of WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). D , E Confocal images of WT and KO retinal sections at ( D ). 2–4 months, and E >1 year stained <t>with</t> <t>anti-secretagogin</t> (Scgn) to label cone bipolar cells (CBCs). Scale bar, 50 μm. F Quantification of total Scgn-positive dendritic sprouting within the ONL in WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). G , H Confocal images of WT and KO retinal sections at G . 2–4 months, and H >1 year stained with anti-PSD95 to label photoreceptor terminals. Scale bar, 50 μm. I Quantification of the PSD95-labeled area within the ONL of WT and KO retina at 2–4 months and >1 year (n = 4 mice per group). J,K . Confocal images of WT and KO retinal sections triple immunolabeled of PKC-α (green), vGlut1 (red), CTBP2 (blue) at ( J ) 2–4 months and ( K ) >1 year. Insets show higher magnification of retracted photoreceptor terminals colocalizing with sprouted RBC dendrites. Scale bar, 50 μm; inset, 5 μm. L , M Confocal images of WT and KO retinal sections triple immunolabeled of secretagogin (green), vGlut1 (blue), and CTBP2 (red) at L 2–4 months and ( M ) >1 year. Insets show higher magnification of retracted cone terminals colocalizing with sprouted CBC dendrites. Scale bar, 50 μm; inset, 5 μm. Error bars are SEM, unpaired t-test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 .
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Image Search Results


A , B Confocal images of retinal sections from WT and α2δ4KO mice at ( A ). 2–4 months, and B >1 year stained with anti-PKC-α to label rod bipolar cells (RBCs). Scale bar, 50 μm. C Quantification of the total length of RBC dendritic sprouting within the ONL of WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). D , E Confocal images of WT and KO retinal sections at ( D ). 2–4 months, and E >1 year stained with anti-secretagogin (Scgn) to label cone bipolar cells (CBCs). Scale bar, 50 μm. F Quantification of total Scgn-positive dendritic sprouting within the ONL in WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). G , H Confocal images of WT and KO retinal sections at G . 2–4 months, and H >1 year stained with anti-PSD95 to label photoreceptor terminals. Scale bar, 50 μm. I Quantification of the PSD95-labeled area within the ONL of WT and KO retina at 2–4 months and >1 year (n = 4 mice per group). J,K . Confocal images of WT and KO retinal sections triple immunolabeled of PKC-α (green), vGlut1 (red), CTBP2 (blue) at ( J ) 2–4 months and ( K ) >1 year. Insets show higher magnification of retracted photoreceptor terminals colocalizing with sprouted RBC dendrites. Scale bar, 50 μm; inset, 5 μm. L , M Confocal images of WT and KO retinal sections triple immunolabeled of secretagogin (green), vGlut1 (blue), and CTBP2 (red) at L 2–4 months and ( M ) >1 year. Insets show higher magnification of retracted cone terminals colocalizing with sprouted CBC dendrites. Scale bar, 50 μm; inset, 5 μm. Error bars are SEM, unpaired t-test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 .

Journal: Cell Death & Disease

Article Title: Dysfunction of α2δ4 leads to photoreceptor degeneration through disrupted synaptic mitochondria and calcium crosstalk

doi: 10.1038/s41419-026-08587-3

Figure Lengend Snippet: A , B Confocal images of retinal sections from WT and α2δ4KO mice at ( A ). 2–4 months, and B >1 year stained with anti-PKC-α to label rod bipolar cells (RBCs). Scale bar, 50 μm. C Quantification of the total length of RBC dendritic sprouting within the ONL of WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). D , E Confocal images of WT and KO retinal sections at ( D ). 2–4 months, and E >1 year stained with anti-secretagogin (Scgn) to label cone bipolar cells (CBCs). Scale bar, 50 μm. F Quantification of total Scgn-positive dendritic sprouting within the ONL in WT and KO mice at 2–4 months and >1 year ( n = 4 mice per group). G , H Confocal images of WT and KO retinal sections at G . 2–4 months, and H >1 year stained with anti-PSD95 to label photoreceptor terminals. Scale bar, 50 μm. I Quantification of the PSD95-labeled area within the ONL of WT and KO retina at 2–4 months and >1 year (n = 4 mice per group). J,K . Confocal images of WT and KO retinal sections triple immunolabeled of PKC-α (green), vGlut1 (red), CTBP2 (blue) at ( J ) 2–4 months and ( K ) >1 year. Insets show higher magnification of retracted photoreceptor terminals colocalizing with sprouted RBC dendrites. Scale bar, 50 μm; inset, 5 μm. L , M Confocal images of WT and KO retinal sections triple immunolabeled of secretagogin (green), vGlut1 (blue), and CTBP2 (red) at L 2–4 months and ( M ) >1 year. Insets show higher magnification of retracted cone terminals colocalizing with sprouted CBC dendrites. Scale bar, 50 μm; inset, 5 μm. Error bars are SEM, unpaired t-test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 .

Article Snippet: The following commercial antibodies were used: mouse anti-PKCα (AB11723, Abcam), rabbit anti-PKCα (P4334, Sigma-Aldrich), rabbit anti-secretagogin (RD181120100, BioVendor), sheep anti-secretagogin (RD184120100, BioVendor), rabbit anti-PSD95 (3450, Cell Signaling Technology), mouse anti-PSD95 (MA1-045, Invitrogen), guinea pig anti-vGlut1 (AB5905, Millipore), mouse anti-CTBP2 (612044, BD Biosciences), rabbit anti-cone arrestin (AB15282, Millipore), mouse anti-MtCo1 (AB14705, Abcam), rabbit anti-RYR-2 ( A34455 , antibodies.com), rabbit anti-IP3R1 (07-1213, Millipore), mouse anti-SERCA2 (MA3-910, Invitrogen), mouse anti-MCU (AMAB91189, Sigma Aldrich), mouse anti-CHOP (2895, Cell Signaling Technology), rabbit anti-phospho-elf2a (3398, Cell Signaling Technology), and rabbit anti-elf2a (5324, Cell Signaling Technology).

Techniques: Staining, Labeling, Immunolabeling